!Name=Induction_MethionineData
!ExptSetNo=6884
!Description=RNA extraction, labeling, and hybridization were performed as in Brauer et al. with slight modifications (Brauer et al., 2008). Samples from chemostat cultures (5 mL) were vacuum-filtered onto 0.45-μm nylon membranes (Millipore, HNWP02500), placed in 2mL locking lid tubes 20 (FisherBrand, 02-681-291), and then flash-frozen in liquid nitrogen. Samples were stored at -80?C until RNA extraction, which was performed with a standard acid-phenol procedure. Crude RNA was cleaned with RNeasy mini columns (QIAGEN, Valencia, CA) prior to mRNA amplification and labeling with the Agilent Quick-Amp Labeling Kit (Part No. 5190-0424). Amplification and labeling were performed per manufacturer?s instructions but with half the volume of each reagent and 0.6 μL of Cy3 or Cy5 dye. Reference RNA was extracted from a lab WT strain (DBY12001) grown to steady state in phosphate-limited (20 mg/L) growth medium at D = 0.18 h-1. Agilent Yeast Oligo V2 microarrays (8x15k) were hybridized for 17 hours at 65?C on a rotisserie at 20RPM. Hybridized microarrays were washed, scanned, and raw data were extracted with Agilent Feature Extractor Software version 9.5. This methionine-limited overexpression dataset consists of 40 microarrays and five separate time courses. For each of 5 TFs (and one GEV-only control, DBY12142) we hybridized mRNA before (t = 0 min) and following (t = 2.5, 5, 15, 30, 45, 60, and 90 min.) addition of 1 μM β-estradiol.
!Name=Jo_Cbf1_DBY12091_1_1-0
!Exptid=115649
!Name=Jo_Cbf1_DBY12091_1_2-2.5
!Exptid=115650
!Name=Jo_Cbf1_DBY12091_1_3-5
!Exptid=115651
!Name=Jo_Cbf1_DBY12091_1_4-15
!Exptid=115652
!Name=Jo_Cbf1_DBY12091_2_1-30
!Exptid=115653
!Name=Jo_Cbf1_DBY12091_2_2-45
!Exptid=115654
!Name=Jo_Cbf1_DBY12091_2_3-60
!Exptid=115655
!Name=Jo_Cbf1_DBY12091_2_4-90
!Exptid=115656
!Name=Met31_DBY12092_1_1-0_MetLimited
!Exptid=115710
!Name=Met31_DBY12092_1_2-2.5
!Exptid=115711
!Name=Met31_DBY12092_1_3-5
!Exptid=115712
!Name=Met31_DBY12092_1_4-15
!Exptid=115713
!Name=Met31_DBY12092_2_1-30
!Exptid=115714
!Name=Met31_DBY12092_2_2-45
!Exptid=115715
!Name=Met31_DBY12092_2_3-60
!Exptid=115716
!Name=Met31_DBY12092_2_4-90
!Exptid=115717
!Name=Met32_DBY12093_1_1-0_MetLimited
!Exptid=115727
!Name=Met32_DBY12093_1_2-2.5_MetLimited
!Exptid=115728
!Name=Met32_DBY12093_1_3-5_MetLimited
!Exptid=115729
!Name=Met32_DBY12093_1_4-15_MetLimited
!Exptid=115730
!Name=Met32_DBY12093_2_1-30_MetLimited
!Exptid=115734
!Name=Met32_DBY12093_2_2-45_MetLimited
!Exptid=115736
!Name=Met32_DBY12093_2_3-60_MetLimited
!Exptid=115738
!Name=Met32_DBY12093_2_4-90_MetLimited
!Exptid=115732
!Name=Met28_DBY12094_1_1-0_MetLimited
!Exptid=115731
!Name=Met28_DBY12094_1_2-2.5_MetLimited
!Exptid=115733
!Name=Met28_DBY12094_1_3-5_MetLimited
!Exptid=115735
!Name=Met28_DBY12094_1_4-15_MetLimited
!Exptid=115737
!Name=Met28_DBY12094_2_1-30_MetLimited
!Exptid=115739
!Name=Met28_DBY12094_2_2-45_MetLimited
!Exptid=115740
!Name=Met28_DBY12094_2_3-60_MetLimited
!Exptid=115741
!Name=Met28_DBY12094_2_4-90_MetLimited
!Exptid=115742
!Name=Jo_Met4_DBY12099_1_1-0
!Exptid=115610
!Name=Jo_Met4_DBY12099_1_2-2.5
!Exptid=115611
!Name=Jo_Met4_DBY12099_1_3-5
!Exptid=115612
!Name=Jo_Met4_DBY12099_1_4-15
!Exptid=115613
!Name=Jo_Met4_DBY12099_2_1-30
!Exptid=115614
!Name=Jo_Met4_DBY12099_2_2-45
!Exptid=115615
!Name=Jo_Met4_DBY12099_2_3-60
!Exptid=115616
!Name=Jo_Met4_DBY12099_2_4-90
!Exptid=115617
!Name=WT_DBY12142_1_1-0_MetLimited
!Exptid=115718
!Name=WT_DBY12142_1_2-2.5_MetLimited
!Exptid=115719
!Name=WT_DBY12142_1_3-5_MetLimited
!Exptid=115720
!Name=WT_DBY12142_1_4-15_MetLimited
!Exptid=115721
!Name=WT_DBY12142_2_1-30_MetLimited
!Exptid=115722
!Name=WT_DBY12142_2_2-45_MetLimited
!Exptid=115723
!Name=WT_DBY12142_2_3-60_MetLimited
!Exptid=115724
!Name=WT_DBY12142_2_4-90_MetLimited
!Exptid=115725
!Name=WT_DBY12142_1_1-120_MetLimited
!Exptid=115726