!Name=BYxRM glucose and ethanol
!ExptSetNo=5446
!Description=This experiment set contains arrays from a quantitative trait locus (QTL) mapping study that was performed in two conditions (glucose and ethanol carbon sources). There are 6 biological replicates of each parent (BY4716 and RM11-1a) grown in each condition. There are also 109 segregants from a cross between BY4716 and RM11-1a that have each been grown in each condition. Finally, there are 2 replacement strains that carry a portion of one parent's genome in the other parent's background (YLK807 = BY4724 + IRA2-RM, YLK810 = RM11-1a + IRA2-BY). Genetic variants influence traits, but their effects can be dependent on environmental and physiological conditions. We sought to understand how this gene-environment interaction works on a molecular level by studying the genetic and molecular basis of variation in gene expression between two yeast strains (BY and RM) grown in two different conditions (glucose and ethanol carbon sources). When we examined these strains, we observed that most transcripts vary by strain and condition, with 2996, 3448, and 2037 transcripts showing significant strain, condition, and strain-condition interaction effects, respectively. Using a collection of segregants derived from a cross between BY and RM, we characterized 1555 linkages for 1382 transcripts that show significant gene-environment interaction. At the locus level, local linkages tend to be more stable across conditions, such that they are more likely show the same effect or the same direction of effect across conditions. Distant linkages are more condition-dependent, and often show effects in different directions in the two conditions. We characterized a locus that influences expression of ribosome biogenesis and energy-metabolism related transcripts, and showed that polymorphism in IRA2 is a major contributor to the variation. Furthermore, the RM allele of IRA2 appears to be more functional than the BY allele across these conditions. This dataset provides a rich resource...
!Name=100E 20_4_c YLK498 1% ethanol
!Exptid=102181
!Name=100g 20_4_c YLK498 2% glucose
!Exptid=102368
!Name=101E 21_1_d YLK507 1% eth
!Exptid=102278
!Name=101g 21_1_d YLK507 2% glucose
!Exptid=102203
!Name=102E 21_2_d YLK511 1% eth
!Exptid=102238
!Name=102g 21_2_d YLK511 2% glucose
!Exptid=102323
!Name=103E 21_3_d YLK515 1% eth
!Exptid=102312
!Name=103g 21_3_d YLK515 2% glucose
!Exptid=102219
!Name=104E 21_4_d YLK519 1% eth
!Exptid=102218
!Name=104g 21_4_d YLK519 2% glucose
!Exptid=102192
!Name=105E 21_5_c YLK522 1% ethanol
!Exptid=102294
!Name=105g 21_5_c YLK522 2% glucose
!Exptid=102314
!Name=106E 22_2_d YLK531 1% eth
!Exptid=102214
!Name=106g 22_2_d YLK531 2% glu
!Exptid=102260
!Name=107E 22_3_b YLK533 1% eth
!Exptid=102266
!Name=107g 22_3_b YLK533 2% glu
!Exptid=102160
!Name=109E 22_5_d YLK543 1% ethanol
!Exptid=102162
!Name=109g 22_5_d YLK543 2% glucose
!Exptid=102226
!Name=10E 2_5_d YLK139 1% eth
!Exptid=102332
!Name=10g 2_5_d YLK139 2% glucose
!Exptid=102140
!Name=110E 23_3_d YLK551 1% ethanol
!Exptid=102120
!Name=110g 23_3_d YLK551 2% glu
!Exptid=102246
!Name=111E 23_5_d YLK559 1% ethanol
!Exptid=102146
!Name=111g 23_5_d YLK559 2% glucose
!Exptid=102369
!Name=112E 24_1_d YLK563 1% ethanol
!Exptid=102337
!Name=112g 24_1_d YLK563 2% glucose
!Exptid=102136
!Name=113E 25_1_d YLK567 1% ethanol
!Exptid=102239
!Name=113g 25_1_d YLK567 2% glu
!Exptid=102292
!Name=114E 25_3_d YLK571 1% ethanol
!Exptid=102264
!Name=114g 25_3_d YLK571 2% glucose
!Exptid=102341
!Name=115E 25_4_d YLK575 1% ethanol
!Exptid=102154
!Name=115g 25_4_d YLK575 2% glu
!Exptid=102324
!Name=116E 26_1_d YLK583 1% eth
!Exptid=102362
!Name=116g 26_1_d YLK583 2% glucose
!Exptid=102130
!Name=117E 26_2_d YLK587 1% eth
!Exptid=102161
!Name=117g 26_2_d YLK587 2% glucose
!Exptid=102347
!Name=11E 2_6_d YLK143 1% eth
!Exptid=102257
!Name=11g 2_6_d YLK143 2% glu
!Exptid=102328
!Name=12E 2_7_a YLK144 1% ethanol
!Exptid=102248
!Name=12g 2_7_a YLK144 2% glucose
!Exptid=102208
!Name=13E 3_1_d YLK151 1% ethanol
!Exptid=102270
!Name=13g 3_1_d YLK151 2% glucose
!Exptid=102311
!Name=15E 3_3_d YLK159 1% ethanol
!Exptid=102237
!Name=15g 3_3_d YLK159 2% glucose
!Exptid=102132
!Name=16E 3_4_d YLK163 1% eth
!Exptid=102333
!Name=16g 3_4_d YLK163 2% glucose
!Exptid=102129
!Name=17E 3_5_d YLK167 1% ethanol
!Exptid=102372
!Name=17g 3_5_d YLK167 2% glucose
!Exptid=102223
!Name=18E 4_1_c YLK170 1% eth
!Exptid=102356
!Name=18g 4_1_c YLK170 2% glu
!Exptid=102338
!Name=1E 1_1_d YLK103 1% ethanol
!Exptid=102304
!Name=1g 1_1_d YLK103 2% glu
!Exptid=102308
!Name=20E 4_3_d YLK179 1% eth
!Exptid=102186
!Name=20g 4_3_d YLK179 2% glucose
!Exptid=102361
!Name=21E 4_4_d YLK183 1% eth
!Exptid=102227
!Name=21g 4_4_d YLK183 2% glucose
!Exptid=102137
!Name=22E 5_1_d YLK187 1% ethanol
!Exptid=102358
!Name=22g 5_1_d YLK187 2% glu
!Exptid=102259
!Name=23E 5_2_d YLK191 1% ethanol
!Exptid=102149
!Name=23g 5_2_d YLK191 2% glu
!Exptid=102280
!Name=24E 5_3_d YLK195 1% ethanol
!Exptid=102151
!Name=24g 5_3_d YLK195 2% glucose
!Exptid=102185
!Name=25E 5_4_d YLK199 1% eth
!Exptid=102228
!Name=25g 5_4_d YLK199 2% glucose
!Exptid=102289
!Name=26E 5_5_d YLK203 1% ethanol
!Exptid=102273
!Name=26g 5_5_d YLK203 2% glucose
!Exptid=102334
!Name=27E 6_1_d YLK207 1% ethanol
!Exptid=102330
!Name=27g 6_1_d YLK207 2% glu
!Exptid=102252
!Name=28E 6_2_b YLK209 1% eth
!Exptid=102298
!Name=28g 6_2_b YLK209 2% glucose
!Exptid=102232
!Name=29E 6_3_c YLK214 1% ethanol
!Exptid=102283
!Name=29g 6_3_c YLK214 2% glu
!Exptid=102165
!Name=30E 6_4_d YLK219 1% eth
!Exptid=102222
!Name=30g 6_4_d YLK219 2% glucose
!Exptid=102204
!Name=31E 6_5_d YLK223 1% eth
!Exptid=102306
!Name=31g 6_5_d YLK223 2% glucose
!Exptid=102131
!Name=32E 6_6_d YLK227 1% eth
!Exptid=102196
!Name=32g 6_6_d YLK227 2% glucose
!Exptid=102157
!Name=33E 6_7_d YLK231 1% ethanol
!Exptid=102360
!Name=33g 6_7_d YLK231 2% glu
!Exptid=102271
!Name=34E 7_1_d YLK235 1% ethanol
!Exptid=102194
!Name=34g 7_1_d YLK235 2% glucose
!Exptid=102327
!Name=35E 7_2_c YLK238 1% eth
!Exptid=102221
!Name=35g 7_2_c YLK238 2% glucose
!Exptid=102307
!Name=36E 7_3_d YLK243 1% ethanol
!Exptid=102143
!Name=36g 7_3_d YLK243 2% glu
!Exptid=102303
!Name=37E 7_4_c YLK246 1% ethanol
!Exptid=102188
!Name=37g 7_4_c YLK246 2% glucose
!Exptid=102187
!Name=38E 7_5_d YLK251 1% ethanol
!Exptid=102225
!Name=38g 7_5_d YLK251 2% glu
!Exptid=102216
!Name=39E 7_6_c YLK254 1% ethanol
!Exptid=102364
!Name=39g 7_6_c YLK254 2% glucose
!Exptid=102141
!Name=3E 1_3_d YLK111 1% eth
!Exptid=102295
!Name=3g 1_3_d YLK111 2% glu
!Exptid=102175
!Name=40E 7_7_c YLK258 1% ethanol
!Exptid=102174
!Name=40g 7_7_c YLK258 2% glu
!Exptid=102345
!Name=41E 7_8_d YLK263 1% eth
!Exptid=102290
!Name=41g 7_8_d YLK263 2% glu
!Exptid=102224
!Name=42E 8_1_a YLK264 1% ethanol
!Exptid=102128
!Name=42g 8_1_a YLK264 2% glucose
!Exptid=102167
!Name=43E 8_2_d YLK271 1% ethanol
!Exptid=102133
!Name=43g 8_2_d YLK271 2% glu
!Exptid=102313
!Name=44E 8_3_a YLK272 1% eth
!Exptid=102285
!Name=44g 8_3_a YLK272 2% glu
!Exptid=102287
!Name=45E 8_4_c YLK278 1% ethanol
!Exptid=102168
!Name=45g 8_4_c YLK278 2% glucose
!Exptid=102365
!Name=46E 8_5_b YLK281 1% ethanol
!Exptid=102215
!Name=46g 8_5_b YLK281 2% glucose
!Exptid=102164
!Name=47E 8_6_c YLK286 1% eth
!Exptid=102250
!Name=47g 8_6_c YLK286 2% glucose
!Exptid=102331
!Name=48E 8_7_b YLK289 1% ethanol
!Exptid=102183
!Name=48g 8_7_b YLK289 2% glucose
!Exptid=102251
!Name=49E 9_1_d YLK295 1% eth
!Exptid=102166
!Name=49g 9_1_d YLK295 2% glucose
!Exptid=102229
!Name=4E 1_4_d YLK115 1% eth
!Exptid=102340
!Name=4g 1_4_d YLK115 2% glu
!Exptid=102243
!Name=50E 9_2_d YLK299 1% ethanol
!Exptid=102144
!Name=50g 9_2_d YLK299 2% glucose
!Exptid=102152
!Name=51E 9_3_d YLK303 1% eth
!Exptid=102255
!Name=51g 9_3_d YLK303 2% glucose
!Exptid=102354
!Name=52E 9_4_d YLK307 1% eth
!Exptid=102189
!Name=52g 9_4_d YLK307 2% glucose
!Exptid=102158
!Name=53E 9_5_d YLK311 1% ethanol
!Exptid=102148
!Name=53g 9_5_d YLK311 2% glu
!Exptid=102269
!Name=54E 9_6_d YLK315 1% ethanol
!Exptid=102335
!Name=54g 9_6_d YLK315 2% glucose
!Exptid=102350
!Name=55E 9_7_d YLK319 1% eth
!Exptid=102182
!Name=55g 9_7_d YLK319 2% glucose
!Exptid=102371
!Name=56E 10_1_c YLK322 1% ethanol
!Exptid=102363
!Name=56g 10_1_c YLK322 2% glu
!Exptid=102343
!Name=57E 10_2_d YLK327 1% ethanol
!Exptid=102117
!Name=57g 10_2_d YLK327 2% glu
!Exptid=102284
!Name=58E 10_3_c YLK330 1% eth
!Exptid=102230
!Name=58g 10_3_c YLK330 2% glucose
!Exptid=102242
!Name=59E 10_4_d YLK335 1% eth
!Exptid=102351
!Name=59g 10_4_d YLK335 2% glucose
!Exptid=102373
!Name=5E 1_5_c YLK118 1% ethanol
!Exptid=102305
!Name=5g 1_5_c YLK118 2% glucose
!Exptid=102322
!Name=60E 11_1_a YLK336 1% ethanol
!Exptid=102254
!Name=60g 11_1_a YLK336 2% glucose
!Exptid=102299
!Name=61E 11_2_d YLK343 1% ethanol
!Exptid=102142
!Name=61g 11_2_d YLK343 2% glucose
!Exptid=102256
!Name=62E 11_3_b YLK345 1% ethanol
!Exptid=102177
!Name=62g 11_3_b YLK345 2% glu
!Exptid=102235
!Name=63E 12_1_d YLK351 1% ethanol
!Exptid=102267
!Name=63g 12_1_d YLK351 2% glucose
!Exptid=102296
!Name=64E 12_2_b YLK353 1% eth
!Exptid=102193
!Name=64g 12_2_b YLK353 2% glu
!Exptid=102272
!Name=65E 13_1_a YLK356 1% ethanol
!Exptid=102355
!Name=65g 13_1_a YLK356 2% glucose
!Exptid=102297
!Name=66E 13_2_c YLK362 1% eth
!Exptid=102195
!Name=66g 13_2_c YLK362 2% glu
!Exptid=102156
!Name=67E 13_3_b YLK365 1% ethanol
!Exptid=102200
!Name=67g 13_3_b YLK365 2% glucose
!Exptid=102339
!Name=68E 13_4_a YLK368 1% ethanol
!Exptid=102346
!Name=68g 13_4_a YLK368 2% glucose
!Exptid=102234
!Name=69E 13_5_c YLK374 1% ethanol
!Exptid=102199
!Name=69g 13_5_c YLK374 2% glucose
!Exptid=102150
!Name=70E 14_1_b YLK377 1% ethanol
!Exptid=102145
!Name=70g 14_1_b YLK377 2% glucose
!Exptid=102315
!Name=71E 14_2_c YLK382 1% eth
!Exptid=102357
!Name=71g 14_2_c YLK382 2% glu
!Exptid=102209
!Name=73E 14_4_a YLK388 1% ethanol
!Exptid=102135
!Name=73g 14_4_a YLK388 2% glu
!Exptid=102349
!Name=74E 14_5_b YLK393 1% ethanol
!Exptid=102258
!Name=74g 14_5_b YLK393 2% glu
!Exptid=102321
!Name=75E 14_6_d YLK399 1% eth
!Exptid=102329
!Name=75g 14_6_d YLK399 2% glucose
!Exptid=102325
!Name=76E 14_7_c YLK402 1% eth
!Exptid=102190
!Name=76g 14_7_c YLK402 2% glucose
!Exptid=102172
!Name=77E 15_2_d YLK407 1% ethanol
!Exptid=102370
!Name=77g 15_2_d YLK407 2% glucose
!Exptid=102291
!Name=78E 15_3_b YLK409 1% eth
!Exptid=102319
!Name=78g 15_3_b YLK409 2% glucose
!Exptid=102153
!Name=79E 15_4_d YLK415 1% eth
!Exptid=102244
!Name=79g 15_4_d YLK415 2% glu
!Exptid=102317
!Name=7E 2_2_d YLK127 1% ethanol
!Exptid=102352
!Name=7g 2_2_d YLK127 2% glu
!Exptid=102336
!Name=80E 15_5_b YLK417 1% ethanol
!Exptid=102310
!Name=80g 15_5_b YLK417 2% glucose
!Exptid=102286
!Name=82E 16_1_d YLK427 1% ethanol
!Exptid=102253
!Name=82g 16_1_d YLK427 2% glucose
!Exptid=102212
!Name=83E 17_1_a YLK428 1% eth
!Exptid=102249
!Name=83g 17_1_a YLK428 2% glucose
!Exptid=102367
!Name=84E 17_2_d YLK435 1% ethanol
!Exptid=102288
!Name=84g 17_2_d YLK435 2% glucose
!Exptid=102171
!Name=85E 17_4_a YLK436 1% eth
!Exptid=102265
!Name=85g 17_4_a YLK436 2% glu
!Exptid=102326
!Name=86E 17_5_b YLK441 1% ethanol
!Exptid=102344
!Name=86g 17_5_b YLK441 2% glu
!Exptid=102207
!Name=87E 18_1_d YLK447 1% ethanol
!Exptid=102191
!Name=87g 18_1_d YLK447 2% glu
!Exptid=102202
!Name=88E 18_2_d YLK451 1% eth
!Exptid=102170
!Name=88g 18_2_d YLK451 2% glucose
!Exptid=102263
!Name=89E 18_3_d YLK455 1% ethanol
!Exptid=102147
!Name=89g 18_3_d YLK455 2% glucose
!Exptid=102118
!Name=8E 2_3_d YLK131 1% eth
!Exptid=102233
!Name=8g 2_3_d YLK131 2% glu
!Exptid=102353
!Name=90E 18_4_c YLK458 1% ethanol
!Exptid=102155
!Name=90g 18_4_c YLK458 2% glu
!Exptid=102316
!Name=92E 19_1_c YLK466 1% ethanol
!Exptid=102318
!Name=92g 19_1_c YLK466 2% glu
!Exptid=102293
!Name=93E 19_2_c YLK470 1% ethanol
!Exptid=102139
!Name=93g 19_2_c YLK470 2% glucose
!Exptid=102247
!Name=94E 19_3_c YLK474 1% ethanol
!Exptid=102261
!Name=94g 19_3_c YLK474 2% glu
!Exptid=102348
!Name=95E 19_4_b YLK477 1% ethanol
!Exptid=102301
!Name=95g 19_4_b YLK477 2% glucose
!Exptid=102197
!Name=96E 19_5_b YLK481 1% eth
!Exptid=102176
!Name=96g 19_5_b YLK481 2% glucose
!Exptid=102231
!Name=97E 20_1_d YLK487 1% ethanol
!Exptid=102163
!Name=97g 20_1_d YLK487 2% glu
!Exptid=102198
!Name=98E 20_2_d YLK491 1% eth
!Exptid=102205
!Name=98g 20_2_d YLK491 2% glucose
!Exptid=102366
!Name=99E 20_3_c YLK494 1% eth
!Exptid=102274
!Name=99g 20_3_c YLK494 2% glucose
!Exptid=102245
!Name=9E 2_4_a YLK132 1% ethanol
!Exptid=102320
!Name=9g 2_4_a YLK132 2% glu
!Exptid=102169
!Name=BY11E BY4716 0 1% eth
!Exptid=102180
!Name=BY11g BY4716 0 2% glucose
!Exptid=102213
!Name=BY1E BY4716 0 1% eth
!Exptid=102236
!Name=BY1g BY4716 0 2% glucose
!Exptid=102206
!Name=BY3E BY4716 0 1% ethanol
!Exptid=102159
!Name=BY3g BY4716 0 2% glucose
!Exptid=102217
!Name=BY5E BY4716 0 1% eth
!Exptid=102302
!Name=BY5g BY4716 0 2% glu
!Exptid=102201
!Name=BY7E BY4716 0 1% eth *repeat*
!Exptid=102359
!Name=BY7g BY4716 0 2% glucose
!Exptid=102210
!Name=BY9E BY4716 0 1% ethanol
!Exptid=102134
!Name=BY9g BY4716 0 2% glucose
!Exptid=102241
!Name=RM11E RM11-1a 0 1% eth
!Exptid=102262
!Name=RM11g RM11-1a 0 2% glucose
!Exptid=102220
!Name=RM1E RM11-1a 0 1% eth
!Exptid=102184
!Name=RM1g RM11-1a 0 2% glu
!Exptid=102342
!Name=RM3E RM11-1a 0 1% ethanol
!Exptid=102240
!Name=RM3g RM11-1a 0 2% glucose
!Exptid=102138
!Name=RM5E RM11-1a 1% ethanol rep 1 vs mixed reference
!Exptid=105754
!Name=RM5g RM11-1a 0 2% glucose
!Exptid=102277
!Name=RM7E RM11-1a 0 1% eth
!Exptid=102178
!Name=RM7g RM11-1a 0 2% glucose
!Exptid=102211
!Name=RM9E RM11-1a 0 1% eth
!Exptid=102309
!Name=RM9g RM11-1a 0 2% glucose
!Exptid=102300
!Name=YLK807 ethanol vs mixed reference
!Exptid=105083
!Name=YLK807 glucose vs mixed reference
!Exptid=105082
!Name=YLK810 ethanol vs mixed reference
!Exptid=105758
!Name=YLK810 glucose vs mixed reference
!Exptid=105763